| Date | Home | Away | Result |
|---|---|---|---|
| 12/09/25 20:15 | Benfica Lisbon | Santa Clara | 1-1 |
| 12/09/25 20:15 | FC Alverca | CD Tondela | 1-0 |
| 13/09/25 15:30 | Moreirense FC | Rio Ave FC | 3-1 |
| 13/09/25 15:30 | Estoril Praia | AVS Futebol SAD | 3-1 |
| 13/09/25 18:00 | FC Porto | Nacional Funchal | 1-0 |
| 13/09/25 20:30 | FC Famalicao | Sporting Lisbon | 1-1 |
| 14/09/25 15:30 | CF Estrela Amadora | Vitoria Guimaraes | --- |
| 14/09/25 18:00 | FC Arouca | Casa Pia AC | --- |
| 14/09/25 20:30 | Sporting Braga | FC Gil Vicente | --- |